Cyclocytidine hydrochloride
CAS No. 10212-25-6
Cyclocytidine hydrochloride( —— )
Catalog No. M10101 CAS No. 10212-25-6
Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
100MG | 33 | In Stock |
|
200MG | 43 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCyclocytidine hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionCyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.
-
DescriptionCyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorDNA/RNA Synthesis
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number10212-25-6
-
Formula Weight261.66
-
Molecular FormulaC9H12ClN3O4
-
Purity>98% (HPLC)
-
SolubilityWater: 44 mg/mL warmed (168.15 mM); DMSO: 52 mg/mL warmed (198.73 mM)
-
SMILESC1=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)OC2=NC1=N.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Doxifluridine
Doxifluridine is a Thymidylate synthase inhibitor.
-
Daptomycin
Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
-
HALOFUGINONE LACTATE
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM.?Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activityhalofuginone (HF), a widely studied derivative of febrifugine, inhibits the development of T(H)17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway.?HF binds glutamyl-prolyl-tRNA synthetase (EPRS), inhibiting prolyl-tRNA synthetase activity;?this inhibition is reversed by the addition of exogenous proline or EPRS.